We introduce a machine learning approach to model checking temporal logic, with application to formal hardware verification. Model checking answers the question of whether every execution of a given system satisfies a desired temporal logic specification. Unlike testing, model checking provides formal guarantees. Its application is expected standard in silicon design and the EDA industry has invested decades into the development of performant symbolic model checking algorithms. Our new approach combines machine learning and symbolic reasoning by using neural networks as formal proof certificates for linear temporal logic. We train our neural certificates from randomly generated executions of the system and we then symbolically check their validity using satisfiability solving which, upon the affirmative answer, establishes that the system provably satisfies the specification. We leverage the expressive power of neural networks to represent proof certificates as well as the fact that checking a certificate is much simpler than finding one. As a result, our machine learning procedure for model checking is entirely unsupervised, formally sound, and practically effective. We experimentally demonstrate that our method outperforms the state-of-the-art academic and commercial model checkers on a set of standard hardware designs written in SystemVerilog.

Knowledge graph entity typing (KGET) aims to infer missing entity type instances in knowledge graphs. Previous research has predominantly centered around leveraging contextual information associated with entities, which provides valuable clues for inference. However, they have long ignored the dual nature of information inherent in entities, encompassing both high-level coarse-grained cluster knowledge and fine-grained type knowledge. This paper introduces Cross-view Optimal Transport for knowledge graph Entity Typing (COTET), a method that effectively incorporates the information on how types are clustered into the representation of entities and types. COTET comprises three modules: i) Multi-view Generation and Encoder, which captures structured knowledge at different levels of granularity through entity-type, entity-cluster, and type-cluster-type perspectives; ii) Cross-view Optimal Transport, transporting view-specific embeddings to a unified space by minimizing the Wasserstein distance from a distributional alignment perspective; iii) Pooling-based Entity Typing Prediction, employing a mixture pooling mechanism to aggregate prediction scores from diverse neighbors of an entity. Additionally, we introduce a distribution-based loss function to mitigate the occurrence of false negatives during training. Extensive experiments demonstrate the effectiveness of COTET when compared to existing baselines.

Clustering in dynamic environments is of increasing importance, with broad applications ranging from real-time data analysis and online unsupervised learning to dynamic facility location problems. While meta-heuristics have shown promising effectiveness in static clustering tasks, their application for tracking optimal clustering solutions or robust clustering over time in dynamic environments remains largely underexplored. This is partly due to a lack of dynamic datasets with diverse, controllable, and realistic dynamic characteristics, hindering systematic performance evaluations of clustering algorithms in various dynamic scenarios. This deficiency leads to a gap in our understanding and capability to effectively design algorithms for clustering in dynamic environments. To bridge this gap, this paper introduces the Dynamic Dataset Generator (DDG). DDG features multiple dynamic Gaussian components integrated with a range of heterogeneous, local, and global changes. These changes vary in spatial and temporal severity, patterns, and domain of influence, providing a comprehensive tool for simulating a wide range of dynamic scenarios.

When tuning software configuration for better performance (e.g., latency or throughput), an important issue that many optimizers face is the presence of local optimum traps, compounded by a highly rugged configuration landscape and expensive measurements. To mitigate these issues, a recent effort has shifted to focus on the level of optimization model (called meta multi-objectivization or MMO) instead of designing better optimizers as in traditional methods. This is done by using an auxiliary performance objective, together with the target performance objective, to help the search jump out of local optima. While effective, MMO needs a fixed weight to balance the two objectives-a parameter that has been found to be crucial as there is a large deviation of the performance between the best and the other settings. However, given the variety of configurable software systems, the "sweet spot" of the weight can vary dramatically in different cases and it is not possible to find the right setting without time-consuming trial and error. In this paper, we seek to overcome this significant shortcoming of MMO by proposing a weight adaptation method, dubbed AdMMO. Our key idea is to adaptively adjust the weight at the right time during tuning, such that a good proportion of the nondominated configurations can be maintained. Moreover, we design a partial duplicate retention mechanism to handle the issue of too many duplicate configurations without losing the rich information provided by the "good" duplicates. Experiments on several real-world systems, objectives, and budgets show that, for 71% of the cases, AdMMO is considerably superior to MMO and a wide range of state-of-the-art optimizers while achieving generally better efficiency with the best speedup between 2.2x and 20x.

Gastric and oesophageal (OG) cancers are the leading causes of cancer mortality worldwide. In OG cancers, recent studies have showed that PDL1 immune checkpoint inhibitors (ICI) in combination with chemotherapy improves patient survival. However, our understanding of the tumour immune microenvironment in OG cancers remains limited. In this study, we interrogate multiplex immunofluorescence (mIF) images taken from patients with advanced Oesophagogastric Adenocarcinoma (OGA) who received first-line fluoropyrimidine and platinum-based chemotherapy in the PLATFORM trial (NCT02678182) to predict the efficacy of the treatment and to explore the biological basis of patients responding to maintenance durvalumab (PDL1 inhibitor). Our proposed Artificial Intelligence (AI) based marker successfully identified responder from non-responder (p < 0.05) as well as those who could potentially benefit from ICI with statistical significance (p < 0.05) for both progression free and overall survival. Our findings suggest that T cells that express FOXP3 seem to heavily influence the patient treatment response and survival outcome. We also observed that higher levels of CD8+PD1+ cells are consistently linked to poor prognosis for both OS and PFS, regardless of ICI.

The adoption of data science brings vast benefits to Small and Medium-sized Enterprises (SMEs) including business productivity, economic growth, innovation and jobs creation. Data Science can support SMEs to optimise production processes, anticipate customers' needs, predict machinery failures and deliver efficient smart services. Businesses can also harness the power of Artificial Intelligence (AI) and Big Data and the smart use of digital technologies to enhance productivity and performance, paving the way for innovation. However, integrating data science decisions into an SME requires both skills and IT investments. In most cases, such expenses are beyond the means of SMEs due to limited resources and restricted access to financing. This paper presents trends and challenges towards an effective data-driven decision making for organisations based on a case study of 85 SMEs, mostly from the West Midlands region of England. The work is supported as part of a 3 years ERDF (European Regional Development Funded project) in the areas of big data management, analytics and business intelligence. We present two case studies that demonstrates the potential of Digitisation, AI and Machine Learning and use these as examples to unveil challenges and showcase the wealth of current available opportunities for SMEs.

Artificial intelligence could eventually help to award scores to the tens of thousands of papers submitted to the Research Excellence Framework by UK universities.Credit: Yuichiro Chino/Getty Researchers tasked with examining whether artificial intelligence (AI) technology could assist in the peer review of journal articles submitted to the United Kingdom's Research Excellence Framework (REF) say the system is not yet accurate enough to aid human assessment, and recommend further testing in a large-scale pilot scheme. The team's findings, published on 12 December, show that the AI system generated identical scores to human peer reviewers up to 72% of the time. When averaged out over the multiple submissions made by some institutions across a broad range of the 34 subject-based'units of assessment' that make up the REF, "the correlation between the human score and the AI score was very high", says data scientist Mike Thelwall at the University of Wolverhampton, UK, who is a co-author of the report. In its current form, however, the tool is most useful when assessing research output from institutions that submit a lot of articles to the REF, Thelwall says. It is less useful for smaller universities that submit only a handful of articles.

COVENTRY, England, April 29, 2022 /CSRwire/ - An article published in WaterWorld magazine outlines how Rockwell Automation (NYSE: ROK) is among a group of global innovators exploring how the United Kingdom's second-largest water company, Severn Trent, can use artificial intelligence and other advanced technologies to improve the region's environmental well-being. The article notes, "The UK's water industry and its regulators agree that climate change, population growth, urban expansion, increasing water consumption, and changing customer behaviors mean that the industry needs solutions that are flexible and capable of adapting to what future demand will throw at them." As part of the endeavor, Rockwell teams specializing in network and cybersecurity, AI, and machine learning applications are providing guidance as well as counsel and support on other emerging technologies. Rockwell software and hardware will also be part of the solution. Rockwell's Mark Watson, account manager, water and wastewater solutions, says the project will demonstrate "how the adoption of AI and machine learning, in addition to access to both real time and historical data, can deliver an intelligent Connected Enterprise application that can be scalable and deployable within the UK water sector."

The fast-spreading information over the internet is essential to support the rapid supply of numerous public utility services and entertainment to users. Social networks and online media paved the way for modern, timely-communication-fashion and convenient access to all types of information. However, it also provides new chances for ill use of the massive amount of available data, such as spreading fake content to manipulate public opinion. Detection of counterfeit content has raised attention in the last few years for the advances in deepfake generation. The rapid growth of machine learning techniques, particularly deep learning, can predict fake content in several application domains, including fake image and video manipulation. This paper presents a comprehensive review of recent studies for deepfake content detection using deep learning-based approaches. We aim to broaden the state-of-the-art research by systematically reviewing the different categories of fake content detection. Furthermore, we report the advantages and drawbacks of the examined works and future directions towards the issues and shortcomings still unsolved on deepfake detection.

In presence of multiple objectives to be optimized in Search-Based Software Engineering (SBSE), Pareto search has been commonly adopted. It searches for a good approximation of the problem's Pareto optimal solutions, from which the stakeholders choose the most preferred solution according to their preferences. However, when clear preferences of the stakeholders (e.g., a set of weights which reflect relative importance between objectives) are available prior to the search, weighted search is believed to be the first choice since it simplifies the search via converting the original multi-objective problem into a single-objective one and enable the search to focus on what only the stakeholders are interested in. This paper questions such a "weighted search first" belief. We show that the weights can, in fact, be harmful to the search process even in the presence of clear preferences. Specifically, we conduct a large scale empirical study which consists of 38 systems/projects from three representative SBSE problems, together with two types of search budget and nine sets of weights, leading to 604 cases of comparisons. Our key finding is that weighted search reaches a certain level of solution quality by consuming relatively less resources at the early stage of the search; however, Pareto search is at the majority of the time (up to 77% of the cases) significantly better than its weighted counterpart, as long as we allow a sufficient, but not unrealistic search budget. This, together with other findings and actionable suggestions in the paper, allows us to codify pragmatic and comprehensive guidance on choosing weighted and Pareto search for SBSE under the circumstance that clear preferences are available. All code and data can be accessed at: https://github.com/ideas-labo/pareto-vs-weight-for-sbse.